Q46: Define the term “cholinergic drugs”?

Apr 8 • Clinical Research Associate, Clinical trail, CRA certification, cracertification_Q&A, cracertification.co.uk • 5134 Views • Comments

Q46: Define the term “cholinergic drugs”?

Answer: Cholinergic means related to the neurotransmitter acetylcholine, and is typically used in a neurological perspective. The parasympathetic nervous system is entirely cholinergic. Neuromuscular junctions, preganglionic neurons of the sympathetic nervous system, the basal forebrain, and brain stem complexes are also cholinergic. In addition, the receptor for the merocrine sweat glands are also cholingergic since acetylocholine is released from post ganglionic symapathic neurons.

A substance is cholinergic if it is capable of producing, altering, or releasing acetylcholine (“indirect-acting”) or mimicking its behaviour at one or more of the body’s acetylcholine receptortypes (“direct-acting”).

Cholinergic drugs are the medications that mimics or enhances the action of the neurotransmitter acetylcholine. Cholinergic drugs are used for urinary retention, myasthenia gravis, glaucoma.

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