Wednesday, May 14, 2025
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Risk of sitting long in a Day @ Work

Reduce the hours of sit prolong life

Stop the leg muscles for the activity causing disturbances in sugar and fat

A study published in the journal “British Medical Journal”showed that the reduction of sitting hours per day to three hours and below would prolong the life of man.

The study, based on investigations conducted in 2005 and 2006, then in the years 2009 and 2010, and included a broad sample of Americans who are over 18 years.

The researchers divided the sample according to the daily sitting hours (less than 3 hours, 3 to 6 hours, and more than six hours), and according to the hours sitting in front of TV (less than two hours, between two hours and 4 hours, more than 4 hours).

The study concluded that “sitting or watching TV for a long time can shorten the life expectancy of the individual in the United States.”

The researchers pointed to the “causal relationship” between the hours supposed to sit down and life expectancy, without scientific proof of that.

The several studies have indicated that lack of physical exertion increases the risk of diabetes, heart disease and increase mortality in general.

He explained lead researcher Dr. Peter Katzmarzyk from the University of Louisiana that “some studies show that in the sitting position, the leg muscles are not active at all, what is causing unrest in the proportion of sugar and fat in the blood.”

The WHO recommends the exercise of at least 150 minutes of exercise per week, to maintain good health.

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What are the risks from exposure to sunlight

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We have workers who are exposed to sunlight, in conditions involving high degrees of risk, sometimes up to 8 times the risk.
We are now in the middle of the summer, where it will be very hot. And We have workers who are exposed to sunlight as part of their work, in conditions involving high degrees of risk, sometimes up to 8 times the risk with the employees in the industry.
There is epidemiological evidence suggests that cancer cells or squamous cell basis linked to a statistically significant exposure to sunlight during work. Develop malignant melanoma, mainly in workers who are exposed to sunlight, even for a few hours, It affects, in general, and essential, neck, face and head.
Continuous exposure to sunlight, except for being considered the main factor in the development of skin cancer, can cause other damages as well, including:
The large number of wrinkles and premature skin aging
The large number of spots on the skin
Excessive production of vitamin D, which increases the risk of the gravel in the kidneys
Injured eyes with cataract
Sun’s rays that cause damage to our health are present, usually, in the field of ultraviolet UV
UV is an electromagnetic radiation, the wavelength shorter than visible light and stored inside the largest amount of energy.
It is important to realize that exposure to sunlight is not necessarily associated with high temperature, as UV rays can penetrate clouds.

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Chiropractic and Pregnancy

Chiropractic is important for pregnant women. Agencies and members of the motherresponsible for her body and the body of the fetus, so the performance of the functions ofher body is perfectly is extremely important for the development of the fetus.
Spine is a flexible rod and a solid, consists of a number of paragraphs that relate to each other and protect the spinal cord and nerve system. Relate to paragraphs in the head with the top and is a focal point with the ribs and back muscles. Can be the backbone wraps and move forward, backward and to the sides. If you look at the spine from the side, we see four arches to increase its natural strength, which maintain balance while standing, as it absorbs shocks and protects them from fractures.During pregnancy changes the backbone building every day, sometimes several times a day, according to the division of the weight and center of gravity in the body of women, hormone levels and change the situation. During pregnancy, women’s weight increases by 15% by weight. These changes lead to changes in posture and loss of balance, which is reflected in dizziness, imbalance and loss of pelvic support of the spine that bears the weight of the body and the fetus.
Chiropractic is important for the expectant mother. Agencies and members of the mother responsible for her body and the body of the fetus, so the performance of the functions of her body is perfectly is very important for the development of the fetus and its growth properly. Many changes occur to the spinal column pain and pelvic area, in order to Taatkiev with increase in the size of the fetus. Because of these changes, the mother becomes vulnerable to a nerve injury to them. Affect the partial dislocation (subluxation – the imbalance between the spine) on your nerves, mainly.
Improvement in some types of exercises Chiropractic during pregnancy the performance of your nerves and provide for the expectant mother and fetus, which is in the process of growth, more healthy environment.
We can look at the implications for the imbalance in the spine at several levels: level Albyumkaniki, hormonal and nervous system. Easy to note that there is a change in the situation and change the center of the body. Result in fetal weight to push the body forward, as it constitutes a burden on the pelvis and spine. Upon approaching the end of pregnancy note a change in the way of walking. But we can not often noted hormonal changes and chemical reactions that occur in the body of the mother in the body of the fetus. My nerves responsible for controlling, on the adequacy of and control all these processes.
Another reason for treatment during pregnancy is to install the pelvic area with the mother.As a result of pressure and trauma faced by the spine and pelvic area during the life of the mother, the entrance to the basin to be flexible and capable of change, which affects the area where the baby comes out through to the outside world.
Know Chiropractic displacement or deviation as a lack of integrity, which falls under the partial dislocation (lack of balance in the paragraphs), which often occurs as a result of trauma and pressure.In addition, the partial dislocation, closing paragraphs, lack of balance in the spine and the pelvis in the mother during pregnancy – all of these factors may cause imbalance of the pelvic muscles and ligaments that connect the joints. The mother’s pelvic support the uterus that grows by a certain ligament. When the pelvic bones are balanced, the uterus grows consistently (symmetrical) with which the fetus grows and develops inside the uterus. When the pelvic bones are Balaauajjaj khul or in part, directly affect the way that you support the uterus. Support the uterus are unevenly by the ligaments can lead to wrap the uterus, and reducing the area where you should live fetus during pregnancy. A term that describes this situation is called “The pressure inside the womb.”
In some cases, this limits the pressure from the place of the fetus during pregnancy and adversely affects the spine and skull of the fetus. Also, restricting the movement of the fetus during pregnancy may lead to prevention of access to the best position for birth. When the skull of the child traveling forward, it refers to the effects of intra-uterine pressure on the movement of the fetus. The baby’s position is sound makes the process of childbirth more difficult task, as it would then be the longest and most painful time and also more likely to need medical interventions.
In many cases, they are resorting to a caesarean section, you lose the mother and fetus are many benefits resulting from a natural birth, through the vagina.
It is worth mentioning that the importance of the backbone of the pregnant mother to double! With the large size of the abdomen and pelvis breadth, the burden grows and body weight on the spine and pelvic area. Center of gravity is changing to become more as Forward, as is the case with the head and neck, while changing the status of the shoulders toward the back. Get friction between the joints of the vertebrae, and increases the burden on the shoulders and the pregnant women suffer from frequent headaches. All of these symptoms can be addressed by medicine. Women may also suffer sometimes from edema in the legs and numbness in the hands.
In addition, the placenta secretes a hormone called “Ralxn” (Relaxin) Uttar his mission to make the pelvic floor tissue and a more flexible approach at the time of birth. But this hormone, unfortunately, influential undesirable, too, as it makes the other tissues more flexible, such as discs between the vertebrae and spinal tissue.
Have pregnant women who receive Chiropractic ability to balance more easily, reducing the number and frequency of friction, inflammation and pain. Allows the basin, which receives specific treatment for pregnant women and birth easier and more comfortable for mom and baby as well. Even after birth, the remaining tissues need strengthening and rehabilitation, after all the months during which he endured all this pressure. Combination of Chiropractic and Exercise Rehabilitation and strengthening the special offers recovery Shaklak and posture before birth, faster.
Chiropractic helps pregnant women who suffer from:
1. Headache
2. Back pain and neck
3. Mother mother legs and along the sciatic nerve
4. Nausea
5. Numbness in hands and feet
Points to ponder:
* Back pain is a common phenomenon during pregnancy, various studies have shown that about 50% of pregnant women suffer from this pain.
* Sense of potential pain during pregnancy is double for women who suffer from back pain.
* Back pain is usually concentrated in the lower back, especially when the sacroiliac joint.Usually increases the severity of pain when walking or standing, especially at the end of the day.
* In most cases, when Zao back pain during pregnancy, it does not stop after birth.
* Pain usually is described as annoying, is a source of concern but it is not sharp.
* Several hypotheses are trying to explain the phenomenon of back pain during pregnancy:- Increasing mechanical pressure.- Hormonal changes.
* Result in increased secretion of estrogen and relaxin to make the ligaments more flexible, as it leads to relaxation of the joints.
* To cope with the increase in the size of the uterus forward, veers back towards the back which increases the curvature of the spine, thus standing, friction and pressure on the sacroiliac joints.
* Excessive movement in the joints of the vertebrae and sacroiliac joint.
* Changes in the feet – including over-pronation (lie), Altstah and pressure – increase the load on the feet.
* Change in movement and lack of balance in the muscles.
* The sacroiliac joint is usually the most balanced of the lumbosacral joint, but it is influenced by the hormone relaxin pregnancy. Estimates are that 70% – 80% of back pain during pregnancy caused by a problem in the performance of this joint.

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Lung cancer Cell Division

Picture from SPL
Lung cancer cell division. Computer artwork of a lung cancer cell during cell division (cytokinesis). The two daughter cells remain temporarily joined by a cytoplasmic bridge (centre). Cancer cells divide rapidly in a chaotic, uncontrolled manner. They may clump to form tumours, which invade and destroy surrounding tissues. Lung cancer is often associated with smoking tobacco and exposure to industrial air pollutants. It causes a cough and chest pain and may spread to other areas of the body. Treatment includes removal of affected parts of the lung, with radiotherapy and chemotherapy.

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Development of a cancer treatment without side effects

Development of a cancer treatment without side effects

A team of Japanese researchers reached an artificial amino acids with a great ability toaccess to cancer cells without harming healthy cells.

According to Radio and Television Japanese “NHK” that researchers at the Institute for Cancer Research, Aichi conducted experiments on cancer cells in the human liver, as well aswhite blood cells and used new types of synthetic amino acids known as CPP44.

It was found that synthetic amino acids penetrated the cells and reduced tumor size by more than half almost, without damaging healthy cells.

and the president of the team Isako conodo tells that it can be very usefull in the field of develloping a cancer cure without side effects.

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Sunlight protects against cancer of the pancreas

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Sunlight protects against cancer of the pancreas

By 49% compared to persons with less sensitive skin

Recent Australian study demonstrated that exposure to sunlight protects against cancer of the pancreas.

The study made by the researcher Rachel Nyali from the Institute of Queensland Medical Research in Australia that the risk of pancreatic cancer decreased in people who have a history of cancer, skin as well as those born in areas with a high level of UV radiation or persons who are allergic to the sun.

The present study in addition to the many conflicting information on the impact of sun exposure on human health and vitamin D received by the body from the sun and the risk of cancer.

Nyali has supported a study of data that suggests that exposure to the sun gives the protectionist impact of cancer of the pancreas.

The researcher said that many of the studies on biology, including those conducted in Australia suggested that people who live in sunny areas always have a lower risk of pancreatic cancer.

While other studies of vitamin D to indicate that exposure to sunlight protects against cancer of the pancreas and that persons who have a high level of vitamin D are more susceptible to disease.

The experiment was conducted between 2007 and 2011, and included 714 people from the area of Queensland Australian who has been compared with a comparison of 709 people assimilated in age and gender.

The researchers found that those most sensitive to the sun have a lower risk of pancreatic cancer by 49% compared to persons with skin less sensitive to the sun.

The researchers also found that the risk of pancreatic cancer less than 40% among people who have a history of skin cancer or other skin diseases arising from exposure to sunlight.

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Breast Feeding improves lung function

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A recent study conducted by researchers from Switzerland and the United Kingdom that breastfeeding improves lung function in children at the age of school entry, especially if they were mothers living with asthma, so as published in the journal “American Journal of Respiratory and Critical Care Medicine” the number of the month of Feb. .

The researchers study and analysis of data for 1458 children, born between 1993 and 1997 in the UK, and assessed the duration of breastfeeding and symptoms of breathing and some measurements of lung function such as “FVC” and “” FEV1 at the age of school entry, and the results showed that children born to mothers infected with asthma improved lung function have dramatically when continued breastfeeding for more than six months.

The study added that this is not the findings of other researchers, adding that breastfeeding may have a direct impact in helping the growth of the lungs, and contrary to what came of these results with previous studies that breastfeeding may be harmful to children born to mothers infected with asthma.

 

and also….

Home Remedies for Breastfeeding

Providing precious moments of bonding between mother and child, the act of breastfeeding is much more than providing nourishment to newborns. Thought a healthier choice for feeding babies, millions of mothers will embrace the emotional and physical challenges of breastfeeding. To make the experience a bit easier, it’s suggested to become more familiar with home remedies for breastfeeding.

breast feeding

COMMON BREASTFEEDING ISSUES

Yes, breast milk is easier for babies to digest than commercial formulas, as it also prevents future food allergies, protects against infections, aids brain development, and encourages the growth of healthy teeth. However, breastfeeding mothers often face an assortment of obstacles and common issues, such as:

• Low Milk Production: A poor diet or medications can lead to low-quality milk or compromised production. Using breast pumps may also slow down milk production, ultimately lowering the amount available for your baby.

• Engorgement: During the first two to three weeks after delivery, some mothers face breast engorgement – when milk excessively fills the breast. Blood and fluid retention add to the overall problem. Women suffering engorgement experience breasts that are hard, tight, tender, full, and tender to touch. The symptoms also make it hard for a baby to latch on and suck.

• Cracked or Sore Nipples [1]: Positioning your baby incorrectly or using damp breast pads can lead to cracked nipples, which can become plagued with redness, irritation, and pain. In some cases, bleeding occurs.

• Plugged Duct: If a baby doesn’t completely empty a breast when feeding, the remaining milk can harden and block the duct. A tight bra can also cause blockage in the ducts. A typical sign of plugged ducts is sore breasts. When left untreated, plugged ducts can turn into mastitis.

• Matitis [2]: When a plugged duct becomes infected, mastitis is the result – causing swollen breasts to fill with bacteria that enter through small cracks found on the nipples. Breasts infected with mastitis are red, painful and secrete pus. Other symptoms include fatigue, vomiting, nausea, and fever.

BREASTFEEDING HOME REMEDIES

If you’ve decided to provide your baby with one of the most natural means of nourishment, prepare yourself for a roller-coaster ride of potential frustration and physical repercussions. To treat common issues that arise, become familiar with the following home remedies for breastfeeding:

 

a) Vitamin E:

Soothe cracked nipples by applying a small amount of vitamin E oil. After nursing, one of the best ways to treat discomfort is to pierce a vitamin E capsule, squeeze out a drop, and rub into the nipple.

b) Hot Compress:

Sometimes, babies are unable to keep up with a mother’s milk production. When faced with overproduction of breast milk, place a hot, wet compress (or washcloth) on the breast to open ducts and allow milk to flow more freely. Additionally, attempt to nurse your baby more often and for longer periods of time to encourage your baby’s appetite.

c) Frequent Nipple Checks:

Checking your nipples on a daily basis can avoid breastfeeding issues, as well as solve current problems. If you spot dry milk on your nipples, use a cotton ball dipped in warm water to remove residue.

d) Baby Positions:

If you place your little one in different positions during each session of breastfeeding, you can prevent the overuse of ducts.

e) Be Gentle to Nipples:

Contrary to popular belief, manipulating or “exercising” the nipples to “toughen up” the skin can wind up doing more damage than good. Proper placement of your baby helps prevent soreness of the nipples.

f) Tea Bags:

When nipples become sore, apply moistened tea bags to reduce the pain. Choose chamomile to control inflammation of the breast.

g) Olive Oil:

Prevent and treat the cracking, tearing and chapping of nipples by rubbing on a small amount of olive oil during the initial weeks of nurses. ??

h) Avoid Soap:

Using soap to clean your nipples leads to excessive dryness, chaps, and cracks. There is no need to use soap, cologne, deodorant or powder on your nipples or breasts – the small bumps located around the areola actually produce oil that contains a natural antiseptic.

i) Aloe Vera:

Treat sore and cracked nipples to fresh aloe vera gel for healing relief.

j) Cumin:

To increase milk production, mix powdered cumin seed and water together to create a paste that also kills germs found in the region. Gently apply the cumin paste over the breasts.

k) Beta-Carotene:

Nursing mothers should increase their intake of foods to receive a high supply of beta-carotene for energy and immune system support. A couple of suggestions include carrots (especially canned carrot juice), spinach (containing the highest among out of all green vegetables), and apricots (as a fruit or juice).

 

Resources

[1] http://www.webmd.com/parenting/features/breastfeeding-sore-nipples
[2] http://pediatrics.about.com/od/breastfeeding/a/mastitis.htm

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Argus II artificail retina

Argus II artificial retina. Researcher holding an Argus II retinal implant electrode array. This 60-electrode array measures 3 by 5 millimetres. Developed by US company Second Sight, it is designed to be implanted in the retina of blind people. Images from an external camera pass to a video processing unit, to an antenna, and then to the retinal implant which stimulates the retina to provide some vision. Users of this implant are able to perceive contrasts between light and dark areas. Photographed at the Institut de la Vision, in Paris, France. Argus II was approved for sale in Europe in 2011.

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HIV Life Cycle

a disease in which there is a severe loss of the body’s cellular immunity, greatly lowering the resistance to infection and malignancy.
AIDS was first identified in the early 1980s and now affects millions of people. The cause is a virus (called the human immunodeficiency virus or HIV) transmitted in blood and in sexual fluids, and although the incubation period may be long and treatment can slow the course of the disease there is currently no cure or vaccine. In the developed world the disease first spread among homosexuals, intravenous drug users, and recipients of infected blood transfusions, before reaching the wider population. This has tended to overshadow a greater epidemic in parts of Africa, where transmission is mainly through heterosexual contact.
And in this picture we are showing you the life cycle of the HIV virus in details.

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What is the relationship between cigarette smoking and the DNA ?

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 Picture From: SPL

Did you know that the damage to genetic material (DNA), get in within minutes of smoking a cigarette? This is shown by a new study conducted in the United States, underscoring the importance of raising awareness among the public about the dangers inherent in tobacco products.
This study showed that smoking leads to damage for immediate and quick, much greater than we envisaged to date. Smoking harms Pal – DNA within minutes of inhalation of smoke.Have been examined by researchers from the University of Minnesota in Minneapolis, the impact of the material contained in cigarette smoke (PAH), which has been proven in the past it carcinogens and it plays a key role in the pathogenesis of lung cancer. Today we knowthat lung cancer is the most common type of cancer that there is a strong relationshipbetween them and the smoking, it also causes the death of 3,000 people in all over the world every day. The study isolated the impact of these materials to the cells of the body,has been canceled so the impact of other factors such as pollution of air, food, etc..

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Gene Therapy

Gene therapy, conceptual image
What is Gene Therapy?Gene therapy is an experimental technique used in treatment of malfunctioning genes, whereby a deficient or defective gene is replaced by a working gene, so that the body can make the proper enzyme or protein and as a result eliminate the origin of the disease.
Gene therapy is therefore targeted to “genetic metabolic diseases” in which a faulty gene causes an enzyme to be either absent or ineffective in catalyzing a particular metabolic reaction effectively.

There are a number of approaches for correcting defective genes:

The most common approach is inserting a gene into a non-specific location within the genome, replacing a nonfunctional gene.
Through selective reverse mutation, the malformed gene can be repaired to attain its normal role.
Via homologous recombination, the normal gene is exchanged for the abnormal gene
Alteration of the regulation of a particular gene.

How does Gene Therapy work?To insert the corrected gene into the patient’s targeted cell, a carrier molecule, called a vector must be used. The most common form of vector is a virus which has been genetically modified to contain human DNA within it. The viruses are modified by replacing the deformed gene with the genes encoding for the desired effect. Thus the virus can be used as a ‘vehicle’ to carry the good genes into the targeted human cell in a pathogenic manner . The target cells are usually a patient’s liver or lung cells, where the viral vector transfers the therapeutic gene into the target cell. The therapeutic gene generates the production of functional proteins and restores the cell to its normal state

The types of viruses used in gene therapyThere are six main types of viruses used as vectors in gene therapy (shown in table below):

1. Retroviruses – A class of viruses that can create double-stranded DNA copies of their RNA genomes. These copies of its genome can be integrated into the chromosomes of host cells. Human immunodeficiency virus (HIV) is a retrovirus.

2. Adenoviruses – A class of viruses with double-stranded DNA genomes that cause respiratory, intestinal, and eye infections in humans. The virus that causes the common cold is an adenovirus.

3. Adeno-associated viruses – A class of small, single-stranded DNA viruses that can insert their genetic material at a specific site on chromosome 19.

4.Herpes simplex viruses – A class of double-stranded DNA viruses that infect a particular cell type, neurons. Herpes simplex virus type 1 is a common human pathogen that causes cold sores.13

5. Alphaviruses- a single stranded positive sense RNA, particularly used to develop viral vectors for  the Ross-River virus, Sindbis virus, Semliki Forest virus and Venezuelan Equine Encephalitis virus.

6. Vaccina or pox viruses- a large, complex, enveloped virus belonging to the poxvirus family. It has a linear, double-stranded DNA genome of approximately 190 kb in length, which encodes for around 250 genes. Can accept as much as 25kb of foreign DNA making it especially useful in expressing a large gene in gene therapy.

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Scientists Modify Viruses For Enhanced Cancer Therapy

Heidelberg, Germany (Scicasts) – Parvoviruses specifically kill cancer cells and are already in the clinical trial stage for treating malignant brain tumours. However, as they can also infect normal cells – without doing any harm to them -, a large portion of viruses is lost during therapy.

Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now modified parvoviruses in such a way that they initially lose their ability to infect cells. In a second step, they equipped the viruses with a molecular key for infecting cancer cells.

A number of parvoviruses are able to enter and destroy cancer cells, while they do not cause any disease symptoms in humans. Since 1992, scientists working with Professor Jean Rommelaere at DKFZ have been studying such viruses with the aim of using them for cancer therapy. For their studies, the researchers chose H1 parvoviruses, which normally infect rodents but are also infectious for human cells. H1 viruses kill tumour cells on the basis of their natural properties, i.e., their genetic material does not need to be modified for them to do so. At Heidelberg University Hospital, a phase I/IIa clinical trial is already ongoing to test treatment of malignant brain tumours using H1 viruses.

“The viruses exclusively destroy cancer cells. But with the same efficiency that they infect cancer cells, they also infect healthy cells. There they do not cause any damage and cannot replicate, but we lose a large portion of therapeutic viruses every time,” says Jean Rommelaere. To solve this problem, the researchers engineered a virus. They first modified the genetic material of the virus in such a way that it loses its ability to infect cells. In a second step, this non-infectious virus was equipped with a molecular key for cancer cells.

Using a computer-based model of the H1 viral protein shell, Antonio Marchini and colleagues from Jean Rommelaere’s department were able to make out how the virus makes contact with cells: It attaches to cell surface proteins that are linked to sialic acid. The researchers then exchanged two amino acids of a viral protein which are instrumental for contact with sialic acid. This minute modification dramatically reduced H1’s capacity to infect cells: In cells treated with the genetically engineered virus, the investigators found not even a tenth of the virus load that would have been expected after infection with unchanged H1.

In a second step, Marchini and colleagues equipped the spike-like protein structures of the viral capsid with three additional amino acids. This enables the viruses to bind to a protein called integrin. This is a cell membrane protein which is typically overexpressed in tumour cells. The reengineered viruses recovered their infectious capacity. Normal cells, which carry little or no integrin, were spared. Melanoma cells, however, which typically produce large amounts of integrin, were infected by the reengineered parvovirus with an efficiency comparable to that of the natural H1 virus.

“This is first evidence that it is basically possible to modify properties of H1 according to a plan. We will surely need several more attempts in order to target the viruses more specifically to cancer cells in the second step. We also already have ideas how to further enhance the infectious capacity and the potential to destroy cancer cells,” says Antonio Marchini.

Xavier Allaume, Nazim El-Andaloussi, Barbara Leuchs, Serena Bonifati, Amit Kulkarni, Tiina Marttila, Johanna K. Kaufmann, Dirk M. Nettelbeck, Jürgen Kleinschmidt, Jean Rommelaere and Antonio Marchini: Retargeting of Rat Parvovirus H-1PV to Cancer Cells through Genetic Engineering of the Viral Capsid. J Virol. April 2012, DOI :10.1128/JVI.06208-11

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